Qëndrim Rijani was born on March 30, 1990, in Kichevo, North Macedonia. He completed his high school education in his hometown and then graduated with a degree in theatre directing from the University of Arts in Tirana. He continued his studies at the same institution, earning a Master's degree in directing and stage performances with a thesis titled "Kitsch and His Claws." He has participated in numerous workshops, and his productions have been featured at international festivals in Russia, Turkey, Hungary, Bosnia and Herzegovina, Switzerland, Kosovo, Albania, North Macedonia, Serbia, and other countries.

He is currently a resident director at the Albanian Theatre in Skopje and a guest lecturer at the University of Arts in Tirana (Albania) and the University of Tetovo (North Macedonia).

So far, he has directed three documentary films, one opera, and twenty-seven professional theatre productions in various theaters, including: Ne vimë për Ajr based on Catastrophic Love Puzzles in OuterO'More (Scott O'Mor), Chapter Two (Neil Simon), Gjymtimi based on A Behanding in Spokane (Martin McDonagh), Doctor Shuster (Dušan Kovačević), Art (Yasmina Reza), The Lying Kind (Anthony Neilson), Ushtria e Ui Tomasit based on Lieutenant of Inishmore (Martin McDonagh), The House of Bernarda Alba (Federico García Lorca), Dinner of Crumbs (Refet Abazi), 39 Hpat based on The 39 Steps (Alfred Hitchcock), Women based on Eight Women (Robert Thomas), Roberto Zucco (Bernard-Marie Koltès), Out at Sea (SławomirIt'sżek), And It's Snowing Outside (Vincenzo Salemme), Hangmen (Martin McDonagh), the opera Skenderbeg, The Threepenny Opera (Bertolt Brecht), Plus 18 based on Edmond (David Mamet & Arian Krasniqi), Të Gjindosurit based on Twelve Angry Men (Reginald Rose), A Whistle in the Dark (Tom Murphy), The Merchant of Venice (William Shakespeare), The Resistible Rise of Arturo Ui (Bertolt Brecht), Three Sisters (Anton Pavlovich Chekhov), Women in the Assembly, Tartuffe (Jean-Baptiste Poquelin Molière), The Lower Depths (Maxim Gorky), Macbeth (William Shakespeare), Körler based on The Blind (Maurice Maeterlinck) and In the Name of Identity (Amin Maalouf).

These productions have collectively won seventy awards. He has received fourteen directing honours, including Director of the Year awards in Albania and North Macedonia, the Performance of the Year award (Kosovo), the Vojdan Černodrinski Award for Best Direction, and the Moisiu Award for Best Direction and Best Performance. Additionally, he was named Artist of the Year by the President of the Republic of North Macedonia.

Rijani will make his directorial debut with the drama premiere of Julius Caesar, which is set to premiere on August 8, 2025, at the new stage near the Silver Gate.